MAR 14, 2018 12:00 PM PDT

Deciphering the Complexities of Neurodegeneration and Neuroinflammation with Gene Expression Profiling

Presented at: Neuroscience 2018
Sponsored by: NanoString Technologies
Speaker

Abstract

Some of the most significant hurdles faced by neuroscientists in the field of neurodegenerative disease research when seeking to acquire genetic information include sample accessibility, reproducibility, efficiency and ease of data analysis. As a proven leader in oncology research and diagnostics, NanoString technology is well-positioned to address the challenges faced by neurodegenerative disease researchers. Because NanoString does not require amplification or the use of enzymes, challenging samples like post-mortem formalin-fixed paraffin embedded (FFPE) tissue can be reliably analyzed to yield reproducible results. Moreover, NanoString offers solutions for single cell and low input samples aimed at getting the most biological information from the smallest sample, including analyte multiplexing. In contrast to other technologies, simple read-outs and data analysis put the results back in the researcher’s hand and serve to expedite the time from experimental design to discovery.  

In this webinar, we will demonstrate the robust performance of the nCounter platform for gene expression profiling of human post-mortem brain specimens, human blood samples and tissue from mouse models of neurodegenerative disease with an emphasis on performance and reproducibility in FFPE samples. Moreover, we will discuss data generated using post-mortem Alzheimer’s and Parkinson’s disease brain tissue that was profiled on our new Neuropathology gene expression panel, which includes 770 curated RNA transcripts. We will demonstrate that this panel allows for a broad and comprehensive assessment of relevant pathways and processes in neurodegenerative disease and explore important biological insights revealed by analyzing these precious samples on the nCounter platform.


Show Resources
You May Also Like
JUN 28, 2022 7:00 AM PDT
JUN 28, 2022 7:00 AM PDT
Date: June 28, 2022 Time: 3:00pm (BST), 4:00pm (CET), 9:00am (CST), 7am (PST) Light-sheet microscopy is an extremely versatile imaging technique with a vast range of implementations that are...
NOV 16, 2022 7:00 PM PST
C.E. CREDITS
NOV 16, 2022 7:00 PM PST
Date: November 16, 2022 Time: 2:00pm (AEST) Date: November 17, 2022 7:00pm (PST), 10:00pm (EST), 4:00am (CET) The growth in FDA-approved cell and gene therapy products for the treatment of d...
AUG 24, 2022 7:00 AM PDT
AUG 24, 2022 7:00 AM PDT
Date: August 24, 2022 Time: 7:00am (PDT), 10:00pm (EDT), 4:00pm (CEST) Light field microscopy was first introduced in 2006, and allows users to capture the 4D light field within the microsco...
JUN 21, 2022 6:00 AM PDT
JUN 21, 2022 6:00 AM PDT
Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
OCT 11, 2022 8:00 AM PDT
C.E. CREDITS
OCT 11, 2022 8:00 AM PDT
Date: October 11, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Multiomic profiling of cell populations at single-cell resolution is revolutionizing scientists’ understanding o...
AUG 16, 2022 11:00 AM PDT
AUG 16, 2022 11:00 AM PDT
Date: August 16, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing pers...
MAR 14, 2018 12:00 PM PDT

Deciphering the Complexities of Neurodegeneration and Neuroinflammation with Gene Expression Profiling

Presented at: Neuroscience 2018
Sponsored by: NanoString Technologies


Show Resources
Loading Comments...
Show Resources