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APR 02, 2020 6:00 AM PDT

Enhanced. Rapid Target Identification by NGS for Vaccine Development

Speaker
  • Market Development, Thermo Fisher Scientific
    Biography
      Cris Kinross graduated in Neuroscience from Allegheny College, where she investigated the molecular role of stress and aging on brain resilience. Her focus on NGS development have contributed to the democratization and simplification of NGS technology.

    Abstract

    Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development. Enhanced options for NGS on Illumina systems now make it possible to identify multiple potentially pathogenic strains of a disease and understand the rate of evolution quickly, with improved precision.

    Two complementary sequencing methods are used to identify targets for vaccine development. Whole-genome sequencing using the Invitrogen Collibri DNA Library Prep Kits provide the entire genomic assembly, offering an improvement over older transposomic methods. Collibri 3ʹ mRNA Library Prep kits provide gene expression insights into pathogen, host and host-pathogen interactions that can be used to refine genomic targets for vaccine development.

     


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