JUN 26, 2019 10:00 AM PDT

Factors to Consider During Adaptation of a Manual Cell Line Development Workflow to Automation

Speaker
  • Development Associate IV, Biological Process Development at Alexion Pharmaceuticals, Inc.
    Biography
      Rob is a Development Associate IV with over 10 years of cell line development experience. He is part of the upstream process development group, leading cell line development and upstream development projects. He has expertise from limited dilution cloning through bioreactor scale up. He is a subject matter expert on multiple high-throughput automated platforms, from microtiter plate liquid handling through high-throughput small scale bioreactor evaluation.

    Abstract

    DATE: June 26, 2019

    TIME:  10:00am PDT

    Mammalian cell line generation is a rate-limiting step in early CMC development and there is a constant desire to increase throughput.  The implementation of automation is one way to increase throughput. This webinar will address some factors to consider during the process of automating a manual workflow including details of culture vessel changes, liquid handling adaptation, and changes of the cell line developer’s job during the process.
    With an end result of increased throughput, automation potentially allows cell line development to begin prior to final molecule selection. This can remove cell line development off the critical path of CMC development.

    Key Learning Objectives:

    • Adjustments required to a manual cell line development workflow to evolve into an automated liquid handling workflow

    • How to optimize pipette tip selection in an automated cell line development workflow

    • How lab roles evolve with the addition of an automated liquid handler

     

    Webinars will be available for unlimited on-demand viewing after live event.

     

    LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.


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