Professor in Neurochemistry, Neurochemistry Laboratory, Amsterdam UMC
BIOGRAPHY
Speaker
Event Date & Time
Date: November 19, 2025
Time: 5:00 AM (PST), 8:00 AM (EST), 2:00 PM (CET)
Abstract
Fluid biomarkers for Alzheimer’s disease (AD) have advanced rapidly during the past several years driven by breakthroughs including development of ultrasensitive and multiplexing technologies and high specificity antibodies. Blood-based biomarkers for AD are being implemented in clinical practice. Fluid biomarkers will play an even more prominent role in clinical care in the future for disorders affecting cognition: for diagnosis, prognosis, treatment monitoring, and treatment development. Multiple fluid biomarkers will need to be measured to capture the complexity of disease mechanisms; measuring diverse pathologies that lead to dementia, and understanding heterogeneity between patients. I will present and discuss these options and discuss recently generated results on the in-house custom Olink Focus 42 Dementia panel and newly available Target 48 Neurodegeneration panels. The focus will be the use for dementia diagnosis and for use in treatments.
Learning Objectives
- Understand the expanding role of fluid biomarkers in diagnosing, monitoring, and treating Alzheimer’s disease and other dementias.
- Discover how multiplexing technologies such as Olink’s Proximity Extension Assay enable sensitive protein measurement to support uncovering diverse disease mechanisms.
- Learn how biomarker panels such as Olink Focus and new Target 48 Neurodegeneration contribute to understanding patient heterogeneity and supporting treatment development.
Webinars will be available for unlimited on-demand viewing after live event.
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