MAR 20, 2014 02:00 PM PDT

Genetics of Parkinsons disease

Presented At Neuroscience
  • Assistant Professor Department of Physiology and Pharmacology, University of the Pacific, Thomas J Long School of Pharmacy and Health Sciences
      Dr. Katerina Venderova obtained her master's and doctorate degrees in pharmacy, and her PhD in Toxicology from Charles University in the Czech Republic. She then received a fellowship from the Parkinson Society Canada and pursued her postdoctoral training at Toronto Western Research Institute (2 years), and subsequently at University of Ottawa in Canada (5 years), where she studied genetics of Parkinson's disease, mechanisms of neuronal death and cell signaling in the basal ganglia. Dr. Venderova joined Pacific in 2011.
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    Parkinsons disease is the most common neurodegenerative movement disorder. Over the past few years, studies have identified a number of genes that cause or contribute to the pathogenesis of this disorder. Pathophysiologically, Parkinsons disease is characterized by a progressive loss of dopaminergic nigrostriatal neurons, a process that to this date cannot be effectively stopped or slowed down by any available pharmacological treatment. A systematic analysis of genes and genetic networks involved in this neurodegenerative process is uncovering new molecular pathways with the hope of identifying potential new pharmacological targets for a disease-modifying treatment of Parkinsons disease. The goal of this presentation is to highlight some of these genes and pathways

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