NOV 14, 2018 8:00 AM PST

Webinar #1: Copy number analysis in transplant research

Sponsored by: Thermo Fisher Scientific
Speaker
  • Assistant Professor, Dept. of Surgery (Division of Transplantation) and Pediatrics, University of Pennsylvania
    Biography
      Brendan Keating, PhD, received his D.Phil. in molecular genetics from the Department of Clinical Medicine at University of Oxford, UK. He completed a post-doctoral fellowship at the Institute of Translational Medicine and Therapeutics at UPenn, and was a visiting Scientist at the Wellcome Trust Sanger Institute, Cambridge, UK. Dr. Keating has designed and developed genomic tools for cardiovascular related studies resulting in over a hundred genetic discoveries in various metabolic and CVD-related traits.
      Dr. Keating joined the Faculty at Penn in 2012, and has his primary appointment in the Division of Transplantation in the Department of Surgery. His major research interests focus on the analyses of miRNA, mRNA and polymorphisms of donor and recipients genomes, with the aim of delivering individualized treatment of immunosuppression therapies post-transplant, and prediction of genetic signals that may underpin graft rejection and complications of rejection. Dr. Keating is Principal Investigator of genome-wide association studies (GWAS) for solid-organ transplant cohorts within the Children's Hospital of Philadelphia, and of a number of urinary omic studies. He instigated the formation of an international genomics consortium (iGeneTRAIN) for large-scale genomic studies using > 50,000 DNA samples from a number of international transplant studies (www.igenetrain.org). Dr. Keating is also a member of the Pharmacogenomics and Return of Results working groups of the NHGRI electronic medical record and genomics (eMERGE) network which is integrating clinical genetic data into patient's electronic medical records for clinical decision support for individualize dosing of patients. Dr. Keating has led or co-authored over 120 genomic publications and has given over 100 presentations in 25 countries including numerous national and international conferences. Dr. Keating is also PI of a prospective NIH-funded study looking at post-transplant outcomes in 12 North American pediatric renal transplant centers.

    Abstract
    DATE: November 14, 2018
    TIME:  08:00am PST, 11:00am EST
     
    International Genetics & Translational Research in Transplantation Network (iGeneTRAIN) has recently generated genome-wide genotyping data on > 50,000 DNA samples from a number of international transplant studies (www.igenetrain.org). The majority of the samples were genotyped in an Axiom array – heavily based on the UK biobank array with additional content specifically tailored for transplantation studies. We have investigated a spectrum of phenotypes and post-transplant outcomes primarily using single-nucleotide polymorphisms (SNPs) but more recently we have begun large-scale copy number variant (CNV) analyses. We will present some of the existing CNV datasets for cause-of-transplant – as well as our ongoing studies in this area using the Axiom CNV software.
     

    Show Resources
    You May Also Like
    MAY 11, 2021 10:00 AM PDT
    C.E. CREDITS
    MAY 11, 2021 10:00 AM PDT
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    DEC 02, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    NOV 16, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 16, 2020 8:00 AM PST
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    MAR 16, 2021 10:00 AM PDT
    C.E. CREDITS
    MAR 16, 2021 10:00 AM PDT
    Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
    DEC 15, 2020 10:00 AM PST
    C.E. CREDITS
    DEC 15, 2020 10:00 AM PST
    DATE: December 15, 2020 TIME: 10:00am PST Scientists from Thermo Fisher Scientific will walk us through the world of microorganisms. They will discuss their most recent research on viruses,...
    NOV 14, 2018 8:00 AM PST

    Webinar #1: Copy number analysis in transplant research

    Sponsored by: Thermo Fisher Scientific

    Specialty

    Molecular Biology

    Cancer Research

    Genetics

    Cell Biology

    Biotechnology

    Clinical Research

    Medicine

    Cancer Diagnostics

    Molecular Diagnostics

    Diagnostics

    Clinical Diagnostics

    Genomics

    Dna

    Immunology

    Biomarkers

    Geography

    North America41%

    Asia23%

    Europe21%

    Africa11%

    South America4%

    Registration Source

    Website Visitors67%

    Email Promotions21%

    WAVE Newsletter Promotion6%

    Social Media Promotions1%

    Client/Sponsor Promotions1%

    Other2%

    Job Title

    Student22%

    Research Scientist16%

    Educator/Faculty10%

    Executive10%

    Medical Doctor/Specialist9%

    Scientist6%

    Facility/Department Manager5%

    Post Doc5%

    Medical Laboratory Technician3%

    Clinical Laboratory Scientist3%

    Biologist3%

    Lab Management3%

    Marketing/Sales2%

    Consultant1%

    Chemist1%

    Organization

    Academic Institution19%

    Hospital12%

    Research Institute12%

    Biotech Company10%

    Medical School8%

    Clinical Laboratory6%

    Life Science Company5%

    Government4%

    Medical Center3%

    Contract Research Organization (Cro)2%

    Non-Profit Organization2%

    Pharmaceutical Company1%

    Ambulatory Care1%

    Industrial Company1%

    Other7%


    Show Resources
    Loading Comments...
    Show Resources
    Attendees
    • See more