SEP 25, 2014 08:00 AM PDT

Grow your LC-MS research and forensic lab profitability with cost-effective analytical workflows

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  • Senior Applications Scientist, Thermo Fisher Scientific
      Joe Di Bussolo earned his B.S. degree in clinical chemistry at West Chester University in 1977. In 1982, he received a Ph.D. degree in biological sciences from Drexel University in Philadelphia. During those college years, Joe worked part time as a medical laboratory technologist at Children's Hospital of Philadelphia. For most of the 20 years that followed, Dr. Di Bussolo helped develop and supported various analytical instruments and software products for the PerkinElmer Corporation. In 2002, Joe joined Cohesive Technologies as an applications scientist. Cohesive was acquired in 2007 by Thermo Fisher Scientific and Joe currently works under the Thermo umbrella as a senior scientist training and collaborating with customers and managing the Applications Laboratory at West Chester University of Pennsylvania. He is also an honorary faculty member and advisor in the University's Pharmaceutical Product Development program.



    This webinar presents LC-MS workflows for cost-effective research and forensic laboratory operation. The workflows, enabled by simple sample preparation coupled with rapid analysis on a 4-channel multiplexing LC system, include quantitation of vitamin D metabolites (25-OH-Vitamin D2 & D3) in blood serum and, methylmalonic acid (MMA) in blood serum for research use, buprenorphine and its metabolite norbuprenorphine in urine, and ethanol metabolites ethyl glucuronide and ethyl sulfate (EtG/EtS) in urine for forensic use. High-throughput data quality and ease of operation for reduced labor costs and consumables cost will be discussed.

    Who Should Attend:

    Forensic toxicologists and clinical researchers who are interested in:


    •    Identification of metabolites in urine and blood serum
    •    LC-MS/MS techniques to resolve more demanding analytes


    Key Learning Objectives:

    •    Principles of LC-MS multiplexing
    •    How to set up methods that maximize sample throughput
    •    How to set up methods that minimize consumables costs
    •    How to set up methods with efficient workflows
    •    What skills are needed for success

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