NOV 02, 2016 12:00 PM PDT

Immunoassays and Pain Management Drug Testing

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  • Director; Siemens Healthineers
      Nihmat Morjana, Ph.D., M.Sc. is a Director at Siemens Healthineers. Dr. Morjana received his Ph.D. in Biochemistry, from Queen's University working on the structure/mechanism and drug interaction of Aldo-Keto Reductases. Following his post-doctoral training at Baylor College of Medicine, he joined Baxter/Dade International/Dade Behring/Siemens. He led projects on the development and commercialization of drugs of abuse, pain management and immunosuppressant immunoassays. Dr. Morjana has 24 years of experience in the diagnostic industry. His current work focus includes immunoassay and application development on multiple-instruments. He is a member of ASBMB, SOFT and AACC and has published peer reviewed papers and abstracts and an inventor on patents. He is on the Editorial Board of Biotechnology and applied Biochemistry and served on the Editorial board of the Internet Journal of Genomics and Proteomics.


    In the past several years, there has been an increase in drug testing associated with chronic pain. Immunoassays are the most common method for initial screening which can test for a specific drug, metabolite, or a class of drugs.  The drug tests are used routinely in the workplace drug testing and periodic testing for drug compliance.  Commercially available immunoassays vary in their features, specificities, and screening thresholds.  Therefore, the results should be looked at with understanding of the immunoassay used in the testing and drug metabolism.  Immunoassays, which are designed for detection of the abuse of drugs, may be suitable for pain management testing.   Immunoassay low cutoff levels may provide laboratories with more sensitive methods for drug monitoring and in identifying abuse and misuse of prescription drugs.  This presentation will discuss immunoassay features, commercial drug tests for opioids/other drugs, and their suitability for pain management testing.

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