JUN 24, 2021 7:00 AM PDT

Improved quantitative understanding of oncological replication kinetics using molecular combing

Sponsored by: Genomic Vision
Speaker

Abstract
Date:  June 24, 2021
Time: 7:00am (PDT),  10:00am (EDT),  4:00pm (CEST)
 
Problem: A comprehensive mechanistic understanding of how genetic alterations impact cancer development and therapeutic insights to cancer are from being fully understood.
 
Solution: Our Genomic Vision Replication Combing Assay (RCA) provides a powerful single DNA- molecule view of replication kinetics at genome-wide resolution, to aid in developing new cancer therapeutics.
 
See how RCA for cancer research provides a clear lens to better understand changes in DNA replication kinetics resulting from specific events such as DNA Polymerase Theta, and how such genome modifications impact efficacy of PARP inhibitors and other treatment regimens. You will leave knowing how molecular combing RCA informs your understanding of the effects genomic variation has on DNA-replication kinetics, within a specific locus or across the genome. This session is your opportunity to recognize the key role molecular combing plays in previewing and monitoring the efficacy of cancer treatment therapies.
 
Learning Objectives:
  • Demonstrate how molecular combing can be applied to your genomic laboratory workflows
  • Outline how molecular combing provides insights to the characterization of DNA replication stress and how the analyses can be used for the drug efficacy
  • Recognize the key role molecular combing plays in previewing and monitoring the efficacy of cancer treatment therapies

 

 
 
  • June 24 - Improved quantitative understanding of oncological replication kinetics using molecular combing - Mario Avarello
    • DNA replication stress and drug efficacy
 
 
Webinars will be available for unlimited on-demand viewing after live event.
 
 

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