MAY 29, 2014 07:30 AM PDT
Is Cervical Cancer a preventable Disease in women? The role of HPV as a screening test.
Presented at the Clinical Diagnostics and Research Virtual Event
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  • Director of Clinical Virology, Serology, and Cellular Immunology, Cleveland Clinic
      Belinda Yen-Lieberman, PhD, is a Professor of Pathology at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University in Cleveland, Ohio. Currently, she is the Medical Director of Clinical and Molecular Virology, Serology, and Cellular Immunology in the Department of Clinical Pathology, Pathology & Laboratory Medicine Institute at the Cleveland Clinic. Dr. Yen-Lieberman has authored more than 100 articles for numerous medical journals on a wide range of topics involving viruses and infectious disease, including studies involving HIV, Hepatitis B , Hepatitis C, Human Papilloma Viruses and Influenza A vaccine, tests for herpes simplex types 1 and 2, respiratory viruses and tuberculosis. Dr. Yen-Lieberman also serves on the Editorial boards of J. of Clinical Virology, J. of Clinical and Vaccine Immunology and J. of Clinical Microbiology.  She has served on the CLIA Subcommittee M53-A on Criteria for Laboratory Testing and Diagnosis of Human Immunodeficiency Virus Infection-Approved Guideline and CLIA MM06-A2 on Quantitative Molecular Methods for Infectious Diseases: Approved Guideline.  She is member of the Advisory Board on the AIDS Clinical Trial Group (ACTG/NIH) Virology Quality Assurance Program and a member of the AIDS Clinical Trial Group (Virology), the CDC HIV Rapid Testing Quality Assurance Workgroup, and the NIAID/NIH Special Emphasis Panel Study Section. Dr. Yen-Lieberman can be reached at 

    Human papillomavirus (HPV) is the primary cause of cervical cancer and more than 100 types of HPV have been identified. Detection of HPV from cervical samples is associated with a 250 times increased risk of high grade cervical neoplasm. Approximately 30 HPV types were reported to infect primarily the squamous epithelium of the lower anogenital tracts of men and women. Worldwide, Cervical Cancer is much more common particularly in countries without screening programs, with an estimated 530,000 new cases of the disease and 275,000 resultant deaths each year (Farlay J, et al. 2008 and Arbyn M, et al 2011). When cervical cancer screening programs have been introduced into communities, marked reductions in cervical cancer incidence have followed (Gustafsson L, et al 1997).

    Human Papillomavirus is one of the most common sexually transmitted infections (STI) in the United States in women, with approximately 6.2 million cases diagnosed annually. The American Cancer Society estimates that there will be 12,170 new cases of cervical cancer in the United States in 2012, with 4,220 deaths from the disease ( Siegel R et al. 2012).

    Learning Objectives:

    At the completion of the presentation, the learners should know:
    1. What is Human Papilloma virus (HPV)
    2. HPV is the primary causal factor of cervical cancer and cervical disease in Women
    3. HPV is one of the most common sexually transmitted infections the the USA
    4. HPV vaccines are available for young men and young women
    5. Why is HPV testing important in women?

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