MAY 31, 2018 07:30 AM PDT

Keynote Presentation: NCATS Automation Capabilities - Where We Are and Where We Are Going

C.E. CREDITS: P.A.C.E. CE | Florida CE
  • Director, Automation and Compound Management at NCATS, NIH
      Sam Michael, a scientist within NCATS Division of Pre-Clinical Innovation, was recently named NIH's Federal Engineer of the Year. He received the honor during a ceremony on February 23, 2012, at the National Press Club in Washington, D.C. The award, sponsored by the National Society of Professional Engineers, was in recognition of his leadership of the establishment of a world-class chemical compound screening facility at NIH.

      As director of automation and compound management at NCATS, Michael and his team create, operate and maintain a suite of automated high-throughput robotic screening systems. These systems enable the development of hundreds of chemical probes that investigators worldwide use to validate new drug targets and chemical leads for development of new drugs for dozens of currently untreatable diseases.


    Over the years high throughput screening has evolved from monolithic static systems to modular more dynamic platforms.  At NCATS the approach taken has been to optimize our existing legacy platforms to make them more dynamic while at the same time pursuing advances in system performance, laboratory sustainability, plate transportation and modular components.

    Learning Objectives: 

    1. To show how many currently existing integrated screening platforms work
    2. To show how they can be modified to enable more complex experiments and future directions for HTS

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