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APR 14, 2021 10:30 AM PDT

Keynote Presentation: New Vaccine and Antiviral Strategies for COVID-19

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Professor, Departments of Microbiology and Medicine, Tisch Cancer Center Icahn School of Medicine at Mount Sinai
    Biography
      Dr. García-Sastre is Professor in the Departments of Microbiology and Medicine and in the Tisch Cancer Center at Icahn School of Medicine Mount Sinai (ISMMS) in New York,. He is also Director of the Global Health and Emerging Pathogens Institute at ISMMS, and Principal Investigator for the Center for Research on Influenza Pathogenesis (CRIP), one of five NIAID Centers of Excellence for Influenza Research and Surveillance (CEIRS). For the past 30 years, his research interest has been focused on the molecular biology, virus-host interactions, innate immunity and pathogenesis of influenza viruses and several other RNA viruses, as well as on the development of new vaccines and antivirals. He has more than 500 peer-reviewed publications in these areas of research. He has been President of the International Society for Vaccines in 2014-2015. He is Editor for the scientific journals PLoS Pathogens, Journal of Virology and Virus Research. In 2017, he has been elected a fellow of the Royal Academy of Pharmacy in Spain. In 2019, he was recognized with a Honorary Doctor Degree from the University of Burgos, Spain. Also in 2019, he was elected a member of the National Academy of Sciences.

    Abstract

    Despite available vaccines and treatments, COVID-19 continues to impose a major burden in the world, as a leading cause of hospitalizations and deaths.  We and others have been working in te identification of novel SARS-CoV-2 inhibitors and vaccines that might have improved efficacy or that can be deployed quickly than those available at this moment.  I will present our preclinical studies on two promising countermeasures against COVID-19, one based on the use of inhibitors of translation as antivirals, the second based on the use of a negative strand RNA virus vector as vaccine.

    Learning Objectives:

    1. Strategies to repurpose drugs for the treatment of COVID-19

    2. Research strategies to conduct preclinical studies on COVID-19 antivirals and vaccines

    3. Use of Newcastle disease virus as a vaccine vector


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