Graduate Research Assistant, University of KentuckyBiography
After completion of a B.S. in Chemistry from Texas A&M University in 2008, Daniel decided to pursue his interests in research in the Department of Pharmaceutical Sciences at the University of Kentucky's College of Pharmacy. He joined the laboratory of Dr. Peixuan Guo, a world-renowned investigator in the area of bionanotechnology, in the fall of 2012. The Guo lab has pioneered the emerging field of RNA nanotechnology, even hosting a new Gordon Research Conference in 2015 dedicated to advancing this fast growing field. Daniel's research interests focus on the construction and manipulation of nanoparticles, composed mainly of RNA, publishing in several high-impact journals (ACS Nano, March 2014; Nucleic Acids Research, May 2014; ACS Nano, June 2014; Methods in Molecular Biology, March 2015). The clinical translation of RNA nanotechnology is hindered by the amounts of purified material needed for treatment. Confronted with this problem, Daniel recently spent time developing approaches for the large-scale production and purification of RNA nanoparticles, especially ultracentrifugation, which acted to retain the integrity and function of the nanostructures (Methods in Molecular Biology; May 2015).