SEP 24, 2014 7:00 AM PDT

Making molecular prosthetics

Speakers
  • Associate Professor of Chemistry, University of Illinois
    Biography
      Professor Burke completed his undergraduate studies at Johns Hopkins University in 1998 and his Ph.D. at Harvard University in 2003. After completing an M.D. at Harvard Medical School, he joined the faculty in the Department of Chemistry at the University of Illinois in June of 2005. His research interests are in the area of organic chemistry with a specific focus on the synthesis and study of small molecules with protein-like functions.

    Abstract:

    Diseases caused by an excess of protein function can often be treated by small molecule inhibitors. In contrast, many diseases caused by missing proteins cannot be addressed with this classic therapeutic strategy. Emerging evidence suggests that small molecules may further possess the capacity to autonomously replicate the functions of many missing proteins, thereby operating as prostheses on the molecular scale. A powerful new building block-based approach for small molecule synthesis is facilitating the systematic study of a variety of small molecules with protein-like functions and thereby brightening the prospects of realizing the substantial potential of this molecular prosthetics approach.


    Show Resources
    You May Also Like
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    FEB 19, 2020 11:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    AUG 27, 2019 9:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 9:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    DEC 05, 2019 9:00 AM PST
    C.E. CREDITS
    DEC 05, 2019 9:00 AM PST
    DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Loading Comments...
    Show Resources