JUL 09, 2020 9:00 AM PDT

Microfluidic-based cell sorting to better sample preparation for 10x Genomics applications

Speakers
  • President and co-Founder at NanoCellect Biomedical, Inc.
    Biography
      José has been developing life science tools and technologies for over 12 years. Most recently, he co-founded NanoCellect Biomedical where he has led teams of engineers and scientists to design, develop, and commercialize cellular analysis and cell sorting technologies. These technologies have been applied to emerging cell engineering workflows and single-cell genomics. Prior to NanoCellect, he co-founded ScholarNexus, a tech accelerator, where he has advised on a wide variety of biotech startup technologies including next-gen sequencing, nanotechnology, and novel drug platforms. José has been part of Amgen's R&D team developing high throughput assays to discover new drug candidates. His post-doctoral research was at UCSD's Laboratory of Bioresponsive Materials where he merged chemical engineering and biology for innovative diagnostic and therapeutic tools. Dr. Morachis received his PhD from UCSD/Salk Institute deciphering transcriptional mechanisms in cancer biology and received his BS in Biochemistry from UC, Riverside
    • Associate Director, Strategic Market Development & Programs, Immunology Segment Marketing, 10x Genomics
      Biography
        Dr. Fritz obtained his PhD in Biomolecular Chemistry from the University of Wisconsin - Madison, and then completed postdoctoral training at the Fred Hutchinson Cancer Research Center in Seattle. Dr. Fritz worked with Illumina and then Adaptive Biotechnologies in a variety of commercial roles before joining 10x Genomics as Senior Product Manager for Single Cell Genomics. Dr. Fritz is now Associate Director, Strategic Market Development & Programs, Immunology Segment Marketing.

      Abstract
      DATE: July 9th, 2020
      TIME:  9:00am PT, 12:00pm ET
       
      Cell sorting is used to separate cells according to their cell size, shape and surface protein expression. Classically used after single cell studies to validate biomarkers expressed on specific cell populations or to verify the existence of a newly identified rare cell population, cell sorting can also be integrated into multiomic workflows for single cell sequencing studies. 
       
      During this webinar we’ll discuss how using cell sorting upstream of single cell RNA sequencing enables you to sensitively and efficiently identify and characterize immune cell interactions. Highlighting a study using cell sorting to identify a small fraction of CD8+ T cells bound to peptide-MHCs, we’ll explore how characterizing only these T cells cells of interest increased the potential to detect rare T cell types and reduced sequencing costs by eliminating the need to sequence all species present in the original sample.
       
      Learning Objectives:
      • Leverage single cell sequencing techniques for multiomic immune profiling analysis
      • View and interpret select single cell sequencing data
      • Optimize sample preparation and cell sorting for generating quality single cell data
       
      Webinars will be available for unlimited on-demand viewing after live event.
       
      LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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