NOV 05, 2019 9:00 AM PST

Minicircle DNA: a new material for CAR-T and AAV vector particles - its development and analysis

Sponsored by: SCIEX
C.E. Credits: Florida CE P.A.C.E. CE
Speaker

Abstract
DATE:  November 5, 2019
TIME:  9:00am PT, 12:00pm ET
 
New results have highlighted the advantages of minicircles over plasmids as they avoid unnecessary bacterial backbone sequences due to higher transfection efficiencies and offer benefits especially in the production of AAV vectors and CAR-T cells.
 
In this webinar we highlight how the manufacturing process, developed in close collaboration with leading experts in the fields of AAV and CAR-T cell-based therapies, meets the requirements of regulating agencies and leads to high quality grade minicircle DNA. We will then highlight how we use capillary electrophoresis (CE) to fully characterize supercoiled ccc-minicircle DNA helping the development of the manufacturing process and maintenance of product quality.
 
Learning Objectives:
  • Outline the development and production process of Minicircle DNA for CAR-T cell therapy.
  • Discover the advantages of Minicircles in AAV vector manufacturing.
  • Demonstrate how capillary electrophoresis (CE) helps ensure the quality of Minicircle DNA.

 

Webinars will be available for unlimited on-demand viewing after live event.
 
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

 

 

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NOV 05, 2019 9:00 AM PST

Minicircle DNA: a new material for CAR-T and AAV vector particles - its development and analysis

Sponsored by: SCIEX
C.E. Credits: Florida CE P.A.C.E. CE

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Cancer Research

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