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MSI Predicts Immunotherapeutic Response

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Professor of Pathology and Oncology, Associate Director, Molecular Diagnostics Laboratory, Johns Hopkins University School of Medicine
    BIOGRAPHY

Abstract

Dr. Eshleman will be discussing how MSI provides a functional readout of mismatch repair status, the implications of mismatch repair deficiency in cancer cells, and how elevated mutation rate associated with MSI-H tumor cells drive the production of neoantigens thought to contribute to immunotherapeutic response.
 

Learning Objectives: 

•    Recall implications of mismatch repair deficiency in solid tumors 
•    Define Key advantages of Long Mononucleotide Repeats (LMRs) in detecting microsatellite instability
 


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