MAR 28, 2023 3:30 AM PDT

Biofluid-based biomarkers for neurological disease

Sponsored by: Bio-Techne
C.E. Credits: P.A.C.E. CE Florida CE

Event Date & Time
Date:  March 28, 2023
Time: 3:30am (PDT),  6:30am (EDT), 12:30pm (CEST)
Biofluid-based neurological biomarkers have shown promise in helping to improve diagnostic accuracy, predict disease progression, and evaluate responses to therapeutic interventions. Neurofilament light- and heavy-chain (NFL, NFH) are cytoskeletal neuronal proteins that are well-suited as biomarkers for neurodegeneration; while basal levels of neurofilaments circulate in both CSF and blood, neurofilament concentrations can rise substantially upon neuronal injury. Because basal NFL levels in serum and plasma are typically in the low picogram per milliliter, sensitive, robust, and reproducible assays are needed to provide high-quality data for monitoring neurodegenerative disease progression and treatment.
In this presentation, attendees will learn how a highly sensitive, automated assay workflow can provide robust, high-quality results on low abundance biomarkers in serum, plasma, and CSF. The discussion will highlight examples of NFL and NFH biomarker profiling related to neurological diseases. Presenters will demonstrate how using, among others highly sensitive, reproducible Simple Plex™ assays provide precise biomarker measurements even at the low levels detected in serum and plasma.
Attendees will learn about:
  • The emerging role of blood-based biomarkers in neurological disease screening and monitoring
  • The challenges and opportunities around creating high sensitivity, high performance biomarker immunoassays
  • Recently published research data using high sensitivity NFL and NFH assays
  • The advantages of the automated Ella immunoassay platform for achieving fast, sensitive, and reproducible biomarker analysis

Learning Objectives:

  • Gain a deeper understanding of the role of biofluid biomarkers in neurological research
  • Review the latest biomarker data using high sensitivity, microfluidics based assays
  • Explore the speed and efficiency advantages of an automated assay workflow
Webinars will be available for unlimited on-demand viewing after live event.
Labroots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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