MENU
AUG 30, 2016 8:00 AM PDT

Optimizing retinal cell differentiation of human pluripotent stem cells for large-scale disease modeling.

Speaker
  • Associate Professor, ARC Future Fellow, Head, Neuroregeneration Research Unit, Centre for Eye Research Australia, University of Melbourne
    Biography
      Dr. Pébay is an Australian Research Council Future Fellow. She obtained her PhD in Neurosciences from the University of Paris VI in 2001 and subsequently joined Professor Martin Pera at Monash University to undertake research on human embryonic stem cells (hESCs). She then continued her research in this area at the University of Melbourne where she commenced in 2007. Since 2012, Dr.Pébay has been appointed to both the Centre for Eye Research Australia and The University of Melbourne. More specifically, Dr. Pébay heads research projects on the identification of signaling mechanisms involved in the maintenance of pluripotency, neural differentiation and more recently cardiac and ocular differentiation of pluripotent stem cells and diseased iPSCs. Her long-term research goal is the establishment of well characterized and efficient protocols for maintenance and differentiation of pluripotent stem cells, suitable for drug screening.

    Abstract
    Human induced pluripotent stem cells (iPSCs) are valuable cells for retinal disease modeling, as these cells are of patient origin and can be differentiated into cell types of interest. This presentation will discuss the differentiation of iPSCs into retinal pigment epithelium cells and retinal ganglion cells and their molecular manipulations for modeling degenerative diseases of the retina and optic nerve.
     

    Show Resources
    You May Also Like
    DEC 16, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 16, 2020 8:00 AM PST
    Date: December 16, 2020 Time: 8:00am (PST), 11:00am (EST) Molecular imaging of living specimens offers a means to draw upon the growing body of high-throughput molecular data to better under...
    JUL 30, 2020 10:00 AM PDT
    C.E. CREDITS
    JUL 30, 2020 10:00 AM PDT
    DATE: July 30, 2020 TIME: 10:00am PT Regenerative medicine has become a key focus worldwide and the number of stem cell, especially pluripotent stem cell (PSC)-based clinical trials are rapi...
    DEC 02, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    DEC 02, 2020 9:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 9:00 AM PST
    DATE: December 2, 2020 TIME: 9:00am PDT Pluripotent stem cell (PSC) research is a continuously evolving field that beholds great promises for the future. The great application potential of P...
    NOV 18, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 18, 2020 8:00 AM PST
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    NOV 16, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 16, 2020 8:00 AM PST
    Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
    Loading Comments...
    Show Resources
    Attendees
    • See more