DEC 06, 2018 6:00 AM CET

Overview of the main hormones associated with alteration of bone and mineral metabolism in patients with chronic kidney disease

Sponsored by: DiaSorin
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Ex head of Laboratoire d'explorations fonctionnelles hôpital Necker-Enfants malades
    Biography
      Now retired (but still active), JCS was the chief of the hormone laboratory in the department of Physiology of the University Necker-Enfants malades hospital in Paris, France, and an invited professor at the Liège University, Belgium. Its main research/clinical topics were the growth hormone/IGFI axis and all aspects of bone and mineral metabolism. He also focused on the importance of vitamin D in many disease other than bone and mineral diseases. He has published more than 300 papers in peer-reviewed journal that are referenced in Pubmed. He was an active member of the scientific committee of the French group of research and information on osteoporosis (GRIO) and a member of the editorial board of several journals.

    Abstract
    DATE: December 6, 2018
    TIME:  6:00am PST, 9:00am EST, 3:00pm CET
     
    Alterations in the bone and mineral metabolism is of great concern in patients with chronic kidney disease (CKD). As the glomerular filtration rate (GFR) decreases, phosphatemia tends to increase while the renal secretion of the active vitamin D metabolite decreases with, consequently, increases in both serum PTH and FGF23 levels. This the pathophysiological basis of the so-called CKD-bone and mineral disorders (MBD). Experts in Nephrology have published international guidelines, called the KDIGO/CKD-MBD, to help the colleagues to deal with these disorders. In this webinar, the KDIGO recommendations concerning the measurement of the serum concentration of PTH, vitamin D metabolites and FGF23 will be discussed.
     
    Learning Objective:
    • Understand the bone metabolic disorder in CKD patients
    • Which is the mechanism that regulate the calcium and phosphorus absorption in patient with altered hormone activities
    • Know the utility of a few fundamental markers to decide the CKD patient management

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