NOV 29, 2018 9:00 AM PST

An overview of primary immune deficiency disorders (PID) and laboratory testing for PID

Sponsored by: Binding Site
  • Assoc. Professor, Dept. of Pediatrics, University of Colorado School of Medicine and Colorado Children's Hospital
      Dr. Vijaya Knight graduated from Mysore Medical College, University of Mysore, India, followed by a residency in Neuromicrobiology and Immunology, National Institutes for Mental Health and Neurosciences, India. She then obtained a PhD in Immunology from Melbourne University, Australia, followed by 3 years of postdoctoral work at the University of California, San Francisco, studying immune evasion by M. tuberculosis in human macrophages. She then spent 2 years as a Juvenile Diabetes Research Foundation fellow at UCSF, working on T cell regulation in models of autoimmune disease. Dr. Knight then transitioned to the biotechnology industry and spent a couple of years a translational research scientist and was involved in biomarker discovery and development and immune monitoring for clinical trials.

      Dr. Knight headed the Advanced Diagnostic Immunology and Flow Cytometry laboratories at National Jewish Health from 2008-2018 and was an Assoc. Professor in the Department of Medicine. In June of 2018, she joined the Dept. of Pediatrics at Children's Hospital, Colorado where she is developing a translational and diagnostic immunology and allergy laboratory. Dr. Knight has been involved for many years in the development of new diagnostic assays for patients with immune deficiency and autoimmune conditions, as well as the development of immune monitoring tools for clinical trials. She is passionate about teaching and has spent many years teaching and mentoring Allery and Clinical Immunology fellows in immunology laboratory methods and interpretation.

      Dr. Knight is an active, contributing member of the Assoc. of Medical Laboratory Immunologists (AMLI), the Clinical Immunology Society (CIS), the American Society for Clinical Pathology (ASCP) and Diagnostic Immunology Resource Committee (through CAP). Dr. Knight has been invited to speak at national and international meetings, chair scientific sessions and develop educational activities in the field of diagnostic immunology.


    DATE: November 29, 2018
    TIME:  9:00AM PST

    An overview of primary immune deficiency disorders (PID) and laboratory testing for PID

    Primary immune deficiencies (PIDs), otherwise known as inborn errors of immunity, are a group of disorders in which a portion of the immune system is missing or is not functioning properly. PIDs result in enhanced susceptibility to infection, often with organisms of low pathogenicity. Additionally, PIDs increase susceptibility to autoimmunity and malignancy. While severe presentations of PID are more readily recognized and referred to tertiary centers for follow up and treatment, more subtle manifestations of PIDs may go unrecognized and untreated. 
    In this webinar, Dr. Knight discusses the basic components of the immune system, when to suspect primary immune deficiency and the current classification of immune deficiencies. Dr. Knight will also discuss the general laboratory workup when immune deficiency is suspected and will also elaborate on phenotypic and functional immunological analysis for specific immune disorders.

    Learning Objectives:

    • Understand the current classification of primary immune deficiencies
    • Understand general recommended laboratory analyses for primary immune deficiencies

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    NOV 29, 2018 9:00 AM PST

    An overview of primary immune deficiency disorders (PID) and laboratory testing for PID

    Sponsored by: Binding Site


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