Practical CFTR Testing To Address Coverage Gaps with the AmplideX® PCR/CE CFTR Kit*

Could your CFTR assay be missing carriers? What if it is missing people of certain genetic ancestries disproportionately? Outdated, ethnically-homogeneous data has historically informed CFTR panel designs, leading to inequitable testing for some ancestries. Learn how recent large-scale diverse population studies provide a greater understanding of the diversity of CFTR variants and how this data has informed the AmplideX PCR/CE CFTR Kit* design to provide the broadest coverage of any targeted CFTR testing kit.

Learning Objectives:

• Report how recent, large-scale population studies have revealed the broad diversity of CFTR mutations within the U.S. population, far beyond the representation of the ~95% Caucasian CFTR2 database
• Recognize that many existing panels may be putting certain populations at risk of false-negative results by overlooking specific variants
• Explain how the AmplideX PCR/CE CFTR Kit* was designed to provide the broadest coverage of any targeted CFTR testing kit based on new data from diverse population studies, while still providing results in a practical and efficient workflow

*For Research Use Only. Not for use in diagnostic procedures.

Content of the AmplideX PCR/CE CFTR Kit panel has been updated since this webinar was recorded.