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MAR 24, 2021 9:00 AM PDT

Residual Nucleic Acid Characterization of Cell Culture-Produced Vaccines and Biologics

Sponsored by: SCIEX
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Speaker
  • Peter Holper, B.S. Biochemistry and Cell Biology
    Applications Scientist, SCIEX
    Biography

      Peter Holper obtained his degree in Biochemistry and Cell Biology from the University of California - San Diego. Peter has over 12 years of experience in biopharma, including as an analytical chemist at Eli Lilly and Company where he was responsible for developing the analytical control strategy for bioproducts. Peter currently works at SCIEX in Redwood City, CA (US) where he is responsible for developing and optimizing CE applications and providing customer demo sample analysis support.

    Abstract
    Date:  March 24, 2021
    Time: 9:00am (PST),  12:00pm (EST)
     
    Determination of residual host cell DNA and RNA are regulatory expectations as they pose potential safety concerns for cell culture-derived vaccines and other biologics. In addition to the quantity of residual DNA or RNA, the size distribution of residual DNA fragments is an important factor related to the oncogenicity and potential for infectivity. Due to the low amount of residual fragments present, developing an assay for with high sensitivity, specificity, and resolution can be a great challenge.
     
    Join Peter Holper from SCIEX to discover a new approach to finding a robust, sensitive sizing method for residual nucleic acid analysis.
     
    Learning Objectives
    • Get introduced to a new approach to analyze residual nucleic acids
    • Learn about key method features that ensure data quality and integrity
    • Discover a platform technique that can cover residual DNA and RNA
     
     
    Webinars will be available for unlimited on-demand viewing after live event.
     
     
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