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DEC 03, 2020 12:00 PM PST

Advancing SARS-CoV-2 Diagnostics Through Standardization and Quantitation

Sponsored by: LGC Seracare
C.E. Credits: P.A.C.E. CE Florida CE
Speakers
  • Chief Scientific Officer, LGC SeraCare
    Biography

      Russell Garlick, PhD, is the Chief Scientific Officer at LGC SeraCare Life Sciences. Since 2012 he has been focusing on expanding the company’s technologies, R&D organization, and product development pipeline. Throughout his career he has worked on the development, regulatory approval, and launch of a variety of technologies and assays, including an HIV/AIDS patient management program, molecular genomics technologies, and HIV drug discovery systems. Prior to joining LGC Clinical Diagnostics, Dr. Garlick was co-founder of Life Sciences Group and served as CEO and CTO of Protein Forest, Inc. He has also held executive R&D positions at PerkinElmer Life Sciences and DuPont NEN Life Sciences.

    • Director, Joint Initiative for Metrology in Biology, Stanford University
      Biography

        Marc Salit, PhD, is the founding director of The Joint Initiative for Metrology in Biology (JIMB) at Stanford University and the SLAC National Accelerator Laboratory. His scientific work is focused on bringing the principles of metrology – systematic measurement science, measurement tool, and standards development – to biology. He brought his background in chemical and physical metrology to challenges in biology in 2003. This translation of metrology has led to innovation in genomic and synthetic biology, with most of that work conducted at the US National Institute of Standards and Technology, where he cofounded and operated consortia like the External RNA Controls Consortium and The Genome in a Bottle Consortium.


      Abstract

      The COVID-19 pandemic continues to have a grip on worldwide health and global economics. Advancing molecular diagnostics is central to the diagnosis and prevention efforts surrounding the deadly SARS-CoV-2 virus. The first presentation is by Marc Salit, Founding Director of The Joint Initiative for Metrology in Biology, Stanford University and leader of the Coronavirus Standards Working Group. CSWG is an international consortium of clinical labs, national measurement labs, IVD manufacturers and IVD organizations. Marc will discuss CSWG efforts to develop tools that ensure the accuracy and reliability of the vital COVID-19 testing enterprise. The second presentation is by Russell Garlick, PhD, CSO at LGC SeraCare. Russell will discuss the emerging need and development of tools for quantitative SARS-CoV-2 viral load testing.

      Learning objectives for Russell Garlick’s presentation:

      1. To review and understand the technical features of qualitative and quantitative SARS-CoV-2 RT-PCR assays

      2. To review clinical applications of SARS-CoV-2 viral load testing for COVID-19 patient management

      Learning objectives for Marc Salit’s presentation:

      1. To recognize clinical molecular SARS-CoV-2 testing as a measurement process with bias and variability at each process element

      2. To learn how control materials and calibration can manage bias and variability through the measurement process


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