NOV 09, 2017 10:30 AM PST

The Need for Serum 25-hydroxyvitamin D Standardization in Clinical and Research Laboratories

C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Coordinator, Vitamin D Standardization Program (VDSP), NIH Office of Dietary Supplements
    Biography
      Christopher T. Sempos, Ph.D., a Nutritional Epidemiologist and Program Director for the Population Studies Program in the NIH Office of Dietary Supplements (ODS) since 2008, retired in July 2015 after more than 27 years of federal government service. Dr. Sempos is now a part-time consultant with ODS who is continuing to serve as coordinator of the Vitamin D Standardization Program (VDSP). VDSP is an international collaborative effort to standardize the laboratory measurement of vitamin D status.

      Dr. Sempos's research areas are in nutritional epidemiology, especially cardiovascular and alcohol epidemiology, nutrition monitoring and public health surveillance methods, dietary survey methods, and biostatistics. Since coming to ODS, his research has focused serum 25-hydroxyvitamin D. The author of more than 100 professional and technical papers, he is also the co-author of the textbook,Statistical Methods in Epidemiology. His work has included numerous papers using data from NHANES including research on iron as a risk factor for heart disease, and national trends in diet and biomarkers of diet.

      Dr. Sempos received his Ph.D. in Nutritional Sciences from the University of Wisconsin-Madison in 1982. At the same time he earned an M.S. in Preventive Medicine-Epidemiology. He completed an NIH postdoctoral fellowship in Biostatistics, Nutrition, Preventive Cardiology and Cardiovascular Epidemiology at the Northwestern University Medical School, Department of Community Health and Preventive Medicine in Chicago, IL, and a postdoctoral fellowship with the U.S. Food and Drug Administration (FDA). From 1999-2004, he was Professor of Epidemiology and Director of Graduate Studies in the Department of Social and Preventive Medicine, University of Buffalo. He also worked in several positions within the Public Health Service from 1983-1999, most notably as Chief, Longitudinal Studies for the Division of Health and Nutrition Examination Surveys (DHANES) at the National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC).

    Abstract:

    This webinar builds and expands on the recent labroots webinar by Dr. Gary Horowitz to emphasize how relatively in expensive assay standardization procedures can be incorporated into clinical and research laboratories.  Serum 25-hydroxyvitamin D [25(OH)D] is a very difficult metabolite to measure.   Assay variation continues to confound the clinical assessment of vitamin D deficiency. The Vitamin D Standardization Program (VDSP) was founded in 2010 by the NIH Office of Dietary Supplements in collaboration with organization and researchers around the world to promote the standardized laboratory measurement of 25(OH)D.  In this webinar, we will discuss the (1) meaning of assay standardization, (2) VDSP Reference Measurement System; (3) Cost-effective Steps to Standardize 25(OH)D Measurement; (4) VDSP Performance Guidelines – A Weakness; and (5) Emerging vitamin D standardization issues.


    Show Resources
    You May Also Like
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    JUN 26, 2018 06:00 AM PDT
    C.E. CREDITS
    JUN 26, 2018 06:00 AM PDT
    Date: June 26, 2018Time: 6:00 a.m. PDT, 9:00 a.m. EDT, 1500 CEST Today’s hematology analyzers employ various methods for enumerating platelets. These methods include: e...
    JUN 20, 2018 10:00 AM EDT
    C.E. CREDITS
    JUN 20, 2018 10:00 AM EDT
    DATE: June 20, 2018TIME: 07:00AM PDT, 10:00AM EDTIntroducing GE’s New Lyo-StableTM service. Sepsis is one of the top challenges facing hospitals in terms of clinical outcomes...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    SEP 12, 2017 08:00 AM PDT
    SEP 12, 2017 08:00 AM PDT
    DATE: September 12, 2017TIME: 8:00am PT, 11:00am ETEvery year, millions of dollars are wasted on poorly characterized and performing antibodies.  Key researchers in the antibody co...
    Loading Comments...