MAR 22, 2022 7:00 AM PDT

Spatio-temporal characterization and quantification of DNA replication events by molecular combing

Sponsored by: Genomic Vision
Speaker

Abstract
Date: March 22, 2022
Time: 7:00am (PDT),  10:00am (EDT),  4:00pm (CEST)
 
DNA replication happens at the very early stage of cell development, at such early stages of development it is important to measure replication kinetics that may be induced by external factors, drug treatments or error by the replication machinery.  The field of studying replication kinetics has become known as DNA Damage and Repair.  In this field it is paramount to understand the Spatio-temporal characterization and quantification of DNA replication events in order to better understand replication kinetics for cancer research and verify the efficacy of a drug and for drug development applications. Our webinar will introduce how Molecular Combing with Replication Combing Assay as a powerful and unique tool that combines the visual (spatio-temporal) with the precise measurement of DNA replication forks kinetics, symmetry, spacing and the quantification of those events at a single DNA molecule resolution across the entire genome.
 
Learning Objectives
  • Understand what molecular combing technology is and how it can detect and characterize DNA replication events such as replication fork speed, symmetry; measure and quantify interorigin and inter termination distances and the number of replication origins at a single DNA molecule resolution across the whole genome.
  • Design experiments for studying DNA Replication and how the Genomic Vision Replication Combing Assay can be used to study the effect of compounds in specific biomarkers to better discriminate the efficacy on a specific pathway to test drug targets and efficiency.
  • Learn how the FiberVision® and Replication Combing Assay workflow can provide a complete solution from sample preparation to data analysis to understand how Molecular Combing technology with our proprietary Replication Combing Assay enables with the precise measurement of DNA replication forks kinetics, symmetry, spacing and the quantification of those events at a single DNA molecule resolution across the entire genome 
 
 
Webinars will be available for unlimited on-demand viewing after live event.
 
 

Show Resources
You May Also Like
MAY 17, 2022 9:00 AM PDT
MAY 17, 2022 9:00 AM PDT
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
DEC 01, 2021 7:00 AM PST
C.E. CREDITS
DEC 01, 2021 7:00 AM PST
Date: December 01, 2021 Time: 7:00am (PST), 10:00am (EST) In the era of immuno-oncology, there is a growing need for the identification of new biomarkers predictive for sensitivity to anti-P...
MAR 16, 2022 8:00 AM PDT
C.E. CREDITS
MAR 16, 2022 8:00 AM PDT
Date: March 16, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CET) Handling of potent and/or hazardous substances is commonplace in sev.....
DEC 09, 2021 11:00 AM PST
C.E. CREDITS
DEC 09, 2021 11:00 AM PST
Date: December 09, 2021 Time: 11:00am (PDT), 2:00pm (EDT) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the need for new...
MAY 19, 2022 8:00 AM PDT
MAY 19, 2022 8:00 AM PDT
Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
MAR 23, 2022 11:00 AM PDT
MAR 23, 2022 11:00 AM PDT
Date: March 23, 2021 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEDT) In this presentation, Dr. Middleton will review the development and deployment of large-scale saliva-based COVID-19 test...
Loading Comments...
Show Resources