APR 29, 2021 4:35 PM CEST

Haematological malignancy samples molecular characterization - in a NGS way

C.E. Credits: P.A.C.E. CE Florida CE
Speaker

Abstract

Next Generation Sequencing (NGS) based molecular tests have been the one of the major focus for the expansion of molecular service provided by Haemato-oncology Diagnostic Service (HODS) in Royal Liverpool University Hospital. The move of NGS platform from Ion PGM to GeneStudio has enabled us to meet the requirement of molecular diagnosis for haematological malignancies. The further move to Genexus system is a way to improve turnaround time and capacity of the NGS tests. With Genexus platform we have been able to expand our NGS test repertoire even further to customised panels.  Customised panel based on Ion Ampliseq technologies provide the flexibility of NGS assay for both molecular diagnosis service and in depth molecular characterisation of haematological malignancy samples At an integrated part of the NGS platform evolution, the data analysis workflow has been optimized and validated to generate clinical relevant variant calling. The use of fusion transcript NGS screening for fusion transcript copy number change has also been explored.

Learning Objectives:

1. S5 evolution of service and benefits of NGS by Genexus

2. Set-up of Genexus in a Molecular Laboratory


Show Resources
You May Also Like
JUN 21, 2022 6:00 AM PDT
JUN 21, 2022 6:00 AM PDT
Date: June 21, 2022 Time: 6:00am (PDT), 9:00am (EDT), 3:00pm (CEST) The global understanding and practice of medicine is currently undergoing a revolutionary change. This shift to precision...
DEC 01, 2021 7:00 AM PST
C.E. CREDITS
DEC 01, 2021 7:00 AM PST
Date: December 01, 2021 Time: 7:00am (PST), 10:00am (EST) In the era of immuno-oncology, there is a growing need for the identification of new biomarkers predictive for sensitivity to anti-P...
MAY 19, 2022 8:00 AM PDT
MAY 19, 2022 8:00 AM PDT
Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
JUN 28, 2022 6:45 AM PDT
JUN 28, 2022 6:45 AM PDT
Date: June 28, 2022 Time: 3:00pm (BST), 4:00pm (CET), 9:00am (CST), 7am (PST) Light-sheet microscopy is an extremely versatile imaging technique with a vast range of implementations that are...
MAR 29, 2022 9:00 AM PDT
C.E. CREDITS
MAR 29, 2022 9:00 AM PDT
Date: March 29, 2022 Time: 09:00am (PDT), 12:00pm (EDT), 17:00 (GMT) Advances in molecular and immunodiagnostics are enabling a personalized, high-precision approach to health in many clin...
DEC 07, 2021 10:00 AM PST
C.E. CREDITS
DEC 07, 2021 10:00 AM PST
Date: December 07, 2021 Time: 10:00am (PST) The RNAscope™ technology allows high sensitivity and spatial resolution providing pivotal single-cell information to gain better insights in...
Loading Comments...
Show Resources