Masahito Kawazu began his medical research after studying medicine at the University of Tokyo and being trained as a hematologist. After earning a degree in research on transcription factors and conducting research on transcriptional regulators as a postdoctoral fellow, he joined Department of Cellular Signaling, The University of Tokyo, in 2010 and started his research on genomic medicine. His research focuses on genomic abnormalities of cancer cells. He aims to find genomic abnormalities that drive the growth of cancer or that affect the immune environment of cancer. He performed a genome analysis of breast cancer and microsatellite instability-high colorectal cancer, and clarified the characteristics of their genomic abnormality. Recently, his team is trying to analyze the abnormal transcripts resulting from the structural variations (chromosomal rearrangement) of cancer genome using a long-read sequencer.