MAY 04, 2016 8:00 AM PDT

Transient Expression: High Cell Density Culture for Increased Protein Production

Speaker
  • Scientist, Teva Pharmaceuticals
    Biography
      Dr. Khandelwal is currently led the critical reagent generation group at the Teva Pharmaceuticals. Puneet group focused on cloning, expression, purification and characterization of recombinant proteins, and evaluate and establish several platform mammalian expression systems. Puneet has vast experience in molecular and cell biology, and is recipient of several fellowships and grants. He received his doctorate from Jawaharlal Nehru University, India and completed postdoctoral fellowship at the University of Pittsburgh School of Medicine.

    Abstract
    The talk will focus on the recent advances in transient protein production using high cell density culture e.g. ExpiCHO, Expi293 for supporting pre-clinical and clinical studies including robust generation of critical reagents for assay support. Comparative studies for several classes of protein including optimization for the expression and quality of difficult-to-express proteins will be highlighted
     

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