FEB 10, 2021 8:00 AM PST

Unveil the immune response to cancer and infectious disease with powerful immunoassays

Speaker
  • Product Development Manager, Thermo Fisher Scientific
    Biography

      Sigrun Badrnya is Manager in Product Development at the Thermo Fisher Scientific Center of Excellence for Immunoassays in Vienna, Austria. Sigrun received her PhD in vascular biology from the Medical University of Vienna in Austria. She continued as postdoctoral researcher at the Karolinska Institute in Stockholm, Sweden and within an industry-academia joint project for Randox Laboratories UK, where she focused on the development of multiplex protein biomarker assays. In her current role she is supervising an R&D team to develop immunoassays across diverse platforms including Invitrogen ELISA, ProcartaPlex and ProQuantum.


    Abstract

    Date:  February 10, 2021

    Time: 8:00am (PST),  11:00am (EST)

     

    Uncovering the interactions between the immune system and cancer cells or pathogens is key for understanding and controlling both cancer and infectious disease. The evolving research field of immuno-oncology focuses on an individual’s immune system as potential innovative treatment approaches to combat cancer. Immune checkpoint molecules have been identified as critical players in the regulation of NK cell- and T cell-mediated immune responses. Thus, the systematic analysis of crucial soluble immune stimulatory and inhibitory factors using multiplexing high-throughput immunoassays will help to shed light on the regulation of checkpoint pathways and to monitor response to immunotherapeutic treatment. Likewise, innovative assay formats to characterize the humoral response to infection are urgently needed as the novel human coronavirus SARS-CoV-2 and the associated respiratory disease COVID-19 continue to evolve worldwide. Simple, rapid and multiplex high-throughput assays will enable researchers to assess the prevalence of SARS-CoV-2 infection and to examine the immunological memory and potential protective immunity of previously infected or vaccinated individuals. Moreover, analyzing the level of a broader panel of immunomodulatory markers will allow researchers to decipher the complex interplay of soluble mediators accounting for the so-called cytokine storm or cytokine release syndrome (CRS), an overactive state of the immune system that is a common complication associated with SARS-CoV-2 infection. Thus, it is of great interest to identify dynamic changes in the immune system in the context of both immuno-oncology research and SARS-CoV-2 infection research for a more holistic view of a subject’s immune status.

     

    Learning Objectives

    • Provide new insights into immunomonitoring approaches to characterize and understand key changes in the immune system associated with cancer and infectious disease
    • Outline immunoassay solutions to advance immuno-oncology research
    • Introduce novel serological assay platforms (RUO) to accurately detect SARS-CoV-2 specific antibodies and support SARS-CoV-2 research

     

     

    Webinars will be available for unlimited on-demand viewing after live event.

     

    LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.


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