APR 08, 2021 10:00 AM EDT

Using Single-Cell Multiomics to Accelerate Cancer Immune Cell Therapy Research

Speaker
  • Science and Technology Advisor, 10x Genomics
    Biography

      Dr. Adriana Suarez is a science and technology advisor at 10x Genomics, where she helps researchers adopt single-cell and spatial technologies to address their scientific questions. She has worked on a wide range of genomics projects in plants and humans. For her Ph.D. at the University of British Columbia, Dr. Suarez explored how different genomic backgrounds affect gene function and expression. She is a strong supporter of inclusive spaces and led the creation of the 1st genomics hackathon in Canada with a focus on inclusivity.


    Abstract

    Cell therapies, including chimeric antigen receptor (CAR) T-cell therapy, are emerging as promising treatments, especially for hematological malignancies. However, many challenges remain in developing this emerging class of therapeutics, from deepening responses in blood-based tumors to expanding efficacy in solid tumors. To face these challenges, understanding the mechanisms behind response, resistance, and toxicity to cell therapies is key. Tools with the resolution and scalability to reveal intra- and inter-patient heterogeneity across cancer types will enable researchers to identify key biomarkers and optimize therapeutic products. Explore how 10x Genomics single-cell solutions can help uncover molecular insights into cell therapeutic efficacy and toxicity, transforming the way we approach immune cell therapies for cancer.


    Show Resources
    You May Also Like
    FEB 24, 2021 10:00 AM PST
    C.E. CREDITS
    FEB 24, 2021 10:00 AM PST
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    DEC 03, 2020 4:30 PM PST
    C.E. CREDITS
    DEC 03, 2020 4:30 PM PST
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    JAN 21, 2021 8:00 AM PST
    JAN 21, 2021 8:00 AM PST
    Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
    NOV 19, 2020 8:00 AM GMT
    C.E. CREDITS
    NOV 19, 2020 8:00 AM GMT
    Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
    NOV 18, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 18, 2020 8:00 AM PST
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    MAR 30, 2021 8:00 AM PDT
    MAR 30, 2021 8:00 AM PDT
    DATE: March 30, 2021 TIME: 08:00am PST In this talk, we will discuss the value of moving towards modular and automated, closed-system technologies designed to enable scalable and cost-effect...
    Loading Comments...
    Show Resources