MAY 30, 2013 8:00 AM PDT

VITROS® Microslide Technologies / Assays

Speakers
  • Director, Scientific Affairs, Ortho Clinical Diagnostics
    Biography
      John Backus, Ph.D. is Director, Scientific Affairs, Ortho Clinical Diagnostics, Part of the Johnson & Johnson Family of Companies. John has 20 years of experience in the In Vitro Diagnostics (IVD) industry. He has held a variety of scientific / managerial positions at Eastman Kodak, Gen-Probe, Sigma, Veridex, and Ortho Clinical Diagnostics, primarily focused on IVD Assay / Technology Development and Clinical Verification and Validation of diagnostic biomarkers to address significant unmet needs in Metabolic Disease, Cardiovascular Disease, Acute Care, Oncology, Reproductive Health, and Infectious Disease. John led the development of the first FDA-approved intra-operative molecular cancer diagnostic and has 13 issued U.S. patents, primarily related to nucleic acid purification, amplification, and detection technologies. John received his Ph.D. in Biochemistry from the University of Rochester. His thesis research focused on elucidation of the RNA sequence elements required for mammalian apoB mRNA editing by the editosome macromolecular complex.

    Abstract:

    VITROS® Microslides utilize a layered, dry-slide technology that enables separate reaction domains such that each step can be optimized to provide excellent assay performance. Excellent precision and accuracy are achieved through designs that combine multiple discrete layers of spreading, masking, scavenger, and other reagent layers. Dry-slide methods use traditional, well-accepted analytical principals and are traceable to accepted reference methods, so that results are consistent over time and around the world. This presentation will focus on three differentiating features of VITROS® Microslide technology: 1) minimization of paraprotein interference in chemistry assays, 2) direct potentiometric measurement of sodium utilizing a disposable ion selective electrode (ISE), and 3) direct measurement of unconjugated, conjugated, and total bilirubin utilizing reflectance spectrophotometry. All three of these features have been demonstrated to improve the clinical/analytical accuracy of assay results.  


    Show Resources
    You May Also Like
    SEP 05, 2019 4:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 4:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    NOV 18, 2019 7:00 AM PST
    C.E. CREDITS
    NOV 18, 2019 7:00 AM PST
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    AUG 27, 2019 9:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 9:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Loading Comments...
    Show Resources