MAY 30, 2013 08:00 AM PDT

VITROS® Microslide Technologies / Assays

Speakers
  • Director, Scientific Affairs, Ortho Clinical Diagnostics
    Biography
      John Backus, Ph.D. is Director, Scientific Affairs, Ortho Clinical Diagnostics, Part of the Johnson & Johnson Family of Companies. John has 20 years of experience in the In Vitro Diagnostics (IVD) industry. He has held a variety of scientific / managerial positions at Eastman Kodak, Gen-Probe, Sigma, Veridex, and Ortho Clinical Diagnostics, primarily focused on IVD Assay / Technology Development and Clinical Verification and Validation of diagnostic biomarkers to address significant unmet needs in Metabolic Disease, Cardiovascular Disease, Acute Care, Oncology, Reproductive Health, and Infectious Disease. John led the development of the first FDA-approved intra-operative molecular cancer diagnostic and has 13 issued U.S. patents, primarily related to nucleic acid purification, amplification, and detection technologies. John received his Ph.D. in Biochemistry from the University of Rochester. His thesis research focused on elucidation of the RNA sequence elements required for mammalian apoB mRNA editing by the editosome macromolecular complex.

    Abstract:

    VITROS® Microslides utilize a layered, dry-slide technology that enables separate reaction domains such that each step can be optimized to provide excellent assay performance. Excellent precision and accuracy are achieved through designs that combine multiple discrete layers of spreading, masking, scavenger, and other reagent layers. Dry-slide methods use traditional, well-accepted analytical principals and are traceable to accepted reference methods, so that results are consistent over time and around the world. This presentation will focus on three differentiating features of VITROS® Microslide technology: 1) minimization of paraprotein interference in chemistry assays, 2) direct potentiometric measurement of sodium utilizing a disposable ion selective electrode (ISE), and 3) direct measurement of unconjugated, conjugated, and total bilirubin utilizing reflectance spectrophotometry. All three of these features have been demonstrated to improve the clinical/analytical accuracy of assay results.  


    Show Resources
    You May Also Like
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    JUN 26, 2018 06:00 AM PDT
    C.E. CREDITS
    JUN 26, 2018 06:00 AM PDT
    Date: June 26, 2018Time: 6:00 a.m. PDT, 9:00 a.m. EDT, 1500 CEST Today’s hematology analyzers employ various methods for enumerating platelets. These methods include: e...
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    JUN 20, 2018 10:00 AM EDT
    C.E. CREDITS
    JUN 20, 2018 10:00 AM EDT
    DATE: June 20, 2018TIME: 07:00AM PDT, 10:00AM EDTIntroducing GE’s New Lyo-StableTM service. Sepsis is one of the top challenges facing hospitals in terms of clinical outcomes...
    APR 25, 2018 07:00 AM PDT
    C.E. CREDITS
    APR 25, 2018 07:00 AM PDT
    DATE: April 25, 2018TIME: 1500 CET, 10:00 a.m. EST, 7:00 a.m. PST Hematology and coagulation laboratories perform a wide range of routine and specialized tests, allowing clinicians to...
    Loading Comments...