APR 25, 2019 1:30 PM PDT

In Vivo Models for Infectious Disease Research Through the Years

  • Senior Manager InVivo Sciences, Charles River
      Matt entered the research field almost 30 years ago as a lab animal technician at the TSI/Mason contract research facility in Worcester, Massachusetts. Since then, he has worked in laboratory contract facilities such as Primedica and OREAD Biosafety, as well as within the biotech/pharma industry at Pharmacia, Pfizer, Genzyme/Sanofi-Aventis, and Biogen. Matt joined Charles River Laboratories last year as the senior manager of the In Vivo Sciences department at their Shrewsbury, Massachusetts facility. During his career, Matt has performed a variety of surgical procedures including device implantation, organ transplants, orthopedic defect, ocular and vascular implants, cardiac procedures, fibrosis modelling and brain and spinal procedures. His experience ranges from mice and rats to non-human primates and livestock. He holds patents for novel surgical devices and implants and has been training technicians, scientists, veterinarians, and physicians in surgical techniques and procedures for over 20 years. He is currently also an adjunct professor at the Worcester Polytechnic Institute, teaching the graduate-level Laboratory Animal Surgery course. Outside of the surgical realm, he has been a toxicology and pharmacology study director, cardiac sonographer, safety pharmacology scientist, and manager. Currently, Matt manages a team of over 70 technicians, trainers, data reviewers, team leaders, and supervisors. Matt served on the board of directors for the Academy of Surgical Research for over ten years, including as the program chair for three years and the educational chair for two years. He is the current president for the New England branch of AALAS.


    Over the past 25 years many advances in techniques have been incorporated into infectious disease research. From genetically modified animals to advances in basic techniques that improve results much has changed. However, many other core principles are just as critical now as they were then and tend to be forgotten in the rush to incorporate new technologies. This presentation will discuss what has changed in the last quarter century for in vivo research including new technologies and techniques as well as point out some critical concepts that deserve to remain in consideration.  

    Learning Objectives: 

    1. Demonstrate the need for a high level of technical skill and understanding to generate high quality data while maintaining the appropriate welfare of our animals
    2. Identify key components for high level study execution

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    In Vivo Models for Infectious Disease Research Through the Years


    Animal Models

    Animal Research


    Laboratory Testing

    Animal Sciences

    Infectious Disease

    Clinical Diagnostics

    Molecular Biology


    Cell Biology



    Veterinary Sciences




    North America40%




    Registration Source

    Website Visitors100%

    Job Title

    Medical Laboratory Technician28%



    Clinical Laboratory Scientist8%

    Research Scientist8%

    Lab Management8%

    Medical Doctor/Specialist5%




    Facility/Department Manager3%

    Animal Care Lab Technician3%


    Academic Institution22%

    Pharmaceutical Company18%

    Clinical Laboratory18%


    Research Institute11%

    Industrial Company2%



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