WEBINAR: ProQuantum high-sensitivity immunoassays offer minimum sample consumption with maximum performance

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Senior R&D Manager and Immunoassay Strategy Lead, Biosciences Division, Thermo Fisher Scientific
    Biography
      David's Ph.D. and postdoctoral work focused on the study of G protein-coupled receptor signaling and thrombosis. Following his academic training, he led multiplexed immunoassay automation efforts at a Luminex® partnering company. In 2009, David joined Thermo Fisher Scientific working on the development of novel immunoassay platforms such as the ProtoPlex™ Immune Response Assay. Now as Sr. Manager and immunoassay strategy lead, David pursues next-gen immunoassay platform development which includes working with translational investigators to identify serum-based biomarkers in cancer, autoimmunity, and inflammation.

    Abstract

    Early detection of protein biomarkers is critical to the study of human diseases, yet current tools available for low-level protein quantitation do not address all the needs for protein and molecular biologists alike. A common concern is sample volume limitation due to difficulties in obtaining sufficient biological samples from various models in research studies. Additionally, cost and time-to-answer are always a factor when considering which assay platform to use. In many cases, end users must make trade-offs on which factors impact their work the least.

    Invitrogen™ ProQuantum™ high-sensitivity immunoassays combine multiple benefits into a single platform so that users don’t need to make trade-offs. The platform works by combining the analyte specificity of high-affinity antibody–antigen binding with the signal detection and amplification of real-time PCR. The result is an assay that can measure low-expressing proteins (femtogram levels) while only consuming a fraction of sample volume (i.e.,1–2 microliters per sample) compared to other immunoassay methods. Best of all, it uses a streamlined workflow (2 hours) that is highly scalable and affordable on an open, widely used qPCR platform.

     

    Learning Objectives:

    • To understand the multiple benefits of ProQuantum high-sensitivity immunoassays and how the platform works
    • To understand how the kits are designed for a simplified workflow amenable to high-throughput applications

    Show Resources
    You May Also Like
    APR 07, 2020 8:00 AM PDT
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    MAY 08, 2020 10:00 AM PDT
    C.E. CREDITS
    MAY 08, 2020 10:00 AM PDT
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    MAY 12, 2020 9:00 AM PDT
    C.E. CREDITS
    MAY 12, 2020 9:00 AM PDT
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    APR 20, 2020 8:00 AM PDT
    C.E. CREDITS
    APR 20, 2020 8:00 AM PDT
    This talk will cover different approaches to emergency hemostasis testing for patients that are actively bleeding due to trauma, surgery, obstetrical emergencies and other causes. The talk i...
    JUN 30, 2020 9:00 AM PDT
    C.E. CREDITS
    JUN 30, 2020 9:00 AM PDT
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    Loading Comments...
    Show Resources
    Attendees
    • See more