JUN 02, 2021 7:30 AM PDT

Panel Presentation: xMAP® INTELLIFLEX and Immunoassay Innovations: Tools to advance immuno-oncology research

Sponsored by: LUMINEX
C.E. Credits: P.A.C.E. CE Florida CE
Speakers

Abstract

Over the past 25 years, Luminex’s xMAP® Technology has emerged as the worldwide leader in bead-based multiplexing. The new xMAP® INTELLIFLEX platform combines the proven performance of xMAP Technology with modern features to enhance performance, empower assay development innovation, and simplify the user experience. No other multiplex platform combines low- and high-plex capabilities, quick time to reliable results, and the ability to acquire data for two parameters per analyte simultaneously. During this session, we will discuss the innovative features of INTELLIFLEX, including the new second reporter channel, which allows users to acquire double the data for each analyte and expand their research further, saving time and precious sample. Immunoassay innovations: Tools to advance immuno-oncology research The evolving field of immuno-oncology focuses on the immune system as the target for innovative treatment approaches to combat cancer. Cancer immunotherapies offer pathways for initiating a self-sustaining cycle of cancer immunity, overcoming tumor evasion mechanisms, and promoting conditions that favor immune protection. Immune checkpoint molecules have been identified as critical players in the regulation of NK cell- and T cell-mediated immune responses. Besides intact transmembrane proteins, soluble isoforms and variants of checkpoint molecules function as immune adjuvants or decoy receptors, and may also influence clinical efficacy of checkpoint modulator drugs. Systematic analysis of these soluble biomarkers should help to shed light on the regulation of checkpoint pathways and facilitate research for future immunotherapeutic treatments. This presentation will provide an overview of immunoassay technologies that enable the simultaneous detection of multiple soluble immune stimulatory and inhibitory factors, as well as a more comprehensive picture of cancer immunity through data analyzed from a blood sample. Find out more at luminexcorp.com/INTELLIFLEX. 

Learning Objectives:

1. Learn about why Luminex’s xMAP bead-based technology is the gold-standard in multiplexing, including how xMAP emerged as the leading multiplexing platform for life science research over the past 25 years.

2. Become familiar with the applications of xMAP Technology, including how it has been used in drug discovery and immunogenicity studies to expand the number of data points per well, accelerating research.

3. Discover the benefits of xMAP INTELLIFLEX—Luminex’s newest xMAP instrument—and the novel second reporter channel, which supports the simultaneous measurement of two reporter fluorophores per analyte in each well.


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