Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
Immunotherapies, including immune checkpoint inhibitors, have emerged as promising treatments for advanced cancers. However, a subset of patients exhibits resistance to such therapies, and t...
Antibodies against ribonucleoprotein (RNP) are an important serologic marker for mixed connective tissue disease (MCTD). RNP interacts with Smith (Sm) proteins to form the Sm/RNP complex. An...
In light of the numerous US FDA-approved humanized monoclonal antibodies (mAbs) for cancer immunotherapy, it is surprising that the advancement of B-cell epitope vaccines designed to elicit...
Cell-based therapeutics show immense promise in treating a variety of currently incurable diseases due to their potent mechanisms. However, despite recent successes, challenges persist in ma...
The recognition of mRNA molecules as a transformative class of therapeutic drugs has soared, particularly with the development of COVID 19 mRNA vaccines. The cancer treatment landscape is si...
Chimeric antigen receptor (CAR) T-cell therapy shows significant potential in treating various human cancers. Unfortunately, researchers have faced difficulty in adapting this therapy to tar...
This presentation looks at the dynamic landscape of therapeutic antibody development, focusing on next-generation immuno-oncology therapeutics that target checkpoint inhibitors and incorpora...
Chimeric antigen receptor (CAR) T cell therapy has emerged as a novel therapeutic option for cancer patients in recent years. Despite its success, this approach faces acknowledged limitation...
Despite the remarkable clinical efficacy of chimeric antigen receptor (CAR) T cells in hematological malignancies, only a subset of patients achieve a durable complete response. Furthermore,...
Nanovials are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell seq...
Chimeric antigen receptor (CAR) T-cell therapy has been extremely successful in treating relapsed/refractory B-cell malignancies, with six CAR T-cell products now FDA approved. Unfortunately...
Circulating proteins found in biofluids represent ideal biomarkers for early disease detection and can be collected non-invasively. Detection from biofluids, however, is challenging as highl...
In the field of tumor immunotherapy, cancer vaccines are designed to help the immune system recognize and attack cancer cells. More efforts are needed to identify neoantigens, develop combin...
Adoptive cell therapy (ACT) is an immunotherapy that employs living immune cells to target and destroy cancer cells. However, the inhibitory tumor microenvironment features several obstacles...
Throughout history, various approaches including surgery, radiation therapy, chemotherapy, and targeted therapy have been employed in the fight against cancer. In the 2010s, the emergence of...
Cell-based therapies are advanced medical treatments for cancers and other diseases. Autologous and allogeneic cell therapies use immune cells from either a patient or from healthy donor sam...
Brain cancer research stands to benefit from the perspectives, tools, and methodologies of non-traditional fields, such as mechanical engineering. Here, I will discuss our engineering-based...
Understanding the spatial organization of the immune response within tumors is crucial for developing effective cancer immunotherapies. In this seminar, we delve into the interactions betwee...
This webinar will demonstrate how the MANTIS and TEMPEST liquid dispensers enable assay automation and miniaturization in various applications such as PCR, NGS, immunoassays, and cell and or...
Abstract: Beginning with a brief historical overview of CRISPR, we will trace its evolution to the current state of gene engineering, highlighting its pivotal role in reshaping the landscape...
Throughout the journey from manufacturing to patient delivery, low efficiency and poor biocompatibility of conventional preservatives are barriers to successful cell preservation. Our webina...
Flow cytometry is a powerful method for the quantification of microorganisms, unparalleled by other technologies. We will (1) give an overview of the benefits and use cases of flow cytometry...
B cell responses within pancreatic ductal adenocarcinoma (PDAC) tumors are associated with improved patient outcomes, yet the specific triggering antigens remain largely unknown. In this web...
Metabolomics research involves two approaches: untargeted analysis, which provides a broad overview of molecular changes but lacks precision, and targeted analysis, which focuses on specific...
The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
Ever wonder what you’re missing in your data? The sheer complexity of today’s flow and mass cytometry datasets demands automated solutions. Machine learning plugins only provide...
The implementation of a preemptive pharmacogenomics (PGx) program in a hospital setting requires a multidisciplinary approach to ensure seamless integration of each stage of the process for...
Immunotherapies, including immune checkpoint inhibitors, have emerged as promising treatments for advanced cancers. However, a subset of patients exhibits resistance to such therapies, and t...
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