Companies / Amerigo Scientific / HIV p24 antigen (recombinant)
Amerigo Scientific

HIV p24 antigen (recombinant) | Amerigo Scientific

HIV-1 p24 is carried in the blood of people infected with HIV.It has been shown that a p24

antigen level of >5 pg/ml is predictive of disease progression with an accuracy comparable

to that of CD4 lymphocyte count (<350 lymphocytes/mm3) and HIV-1 RNA viral load >30,000

copies/ml, which are cut-offs used in guidelines for the initiation of antiretroviral therapy.Viral capsid protein p24 plays important roles in HIV pathogenesis. Peptides and small

molecule inhibitors targeting p24 have shown to inhibit virus replication in treated cells.

The p24 capsid protein plays important roles in both early and late stages of HIV-1 replication

cycle. During the virus particle assembly, capsid domains interact with Gag polyprotein that

undergoes proteolytic cleavage and transforms the immature particles to mature virions.

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ABOUT THE COMPANY

Amerigo Scientific is a distribution company focused on providing critical products and services to the biomedical and life science research communities. Although a new company, Amerigo Scientific's founder has had more than 20 years of rich experience in the biomedical and biochemical fields, and has established close contacts with key personnel in...
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