High-Throughput Clone Screening Under Manufacturing-Relevant Conditions with the Cydem VT System

Cell line development (CLD) is often a critical bottleneck in biopharmaceutical production, often requiring labor-intensive workflows and multiple sequential screening steps that extend timelines and increase risk of advancing suboptimal clones or overlooking top performers. The Cydem VT Automated Clone Screening System addresses these challenges by combining high-throughput capacity with bioreactor-like control, enabling earlier and more predictive screening under pH- and DO-controlled fed-batch conditions- while reducing workload through fully integrated automation.

In this webinar, we will present results from collaborative studies demonstrating how the Cydem VT system:

· Achieves high concordance with traditional minipool screening while reducing hands-on labor by up to 90%

· Consolidates clone screening steps to shorten development timelines

· Improves decision-making by delivering manufacturing-relevant answers earlier

· Translates results reliably across systems and scales

By introducing precise environmental control earlier in the CLD workflow in a high-throughput, automated capacity, the Cydem VT system enables researchers to evaluate more clones in less time, improve selection confidence, and accelerate development timelines—all while freeing scientists to focus on higher-value tasks.