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BOC Sciences

(Des-Glu22)-Amyloid _-Protein (1-40) | BOC Sciences

Osaka mutation is the first deletion type mutation found in APP and A_. A_ E22delta mutant is more resistant to degradation of two major A_-degrading enzymes, neprilysin and insulin-degrading enzyme. The synthetic mutant A_ has unusual aggregation properties, with enhanced oligomerization but no fibrillization. It inhibits long-term hippocampal enhancement more effectively than wild-type A_.

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BOC Sciences specializes in small molecule synthesis, biosynthesis, purification, and characterization. It provides a wide range of research chemicals and biochemicals, including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecules and chiral compounds.