[Leu27]-Melan-A, MART 1 (26-35) is an analog of MART-1 (26-35), which is an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein. [Leu27]-Melan-A MART 1 (26-35) shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural MART 1 (26-35).