Name: "shRNA Adeno-associated Virus Serotype 2, pU6-(JOSD2-shRNA-Seq1)"
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"shRNA Adeno-associated Virus Serotype 2, pU6-(JOSD2-shRNA-Seq1)" | Creative Biolabs

This product is a JOSD2-shRNA encoding AAV, which is based on AAV-2 serotype. The JOSD2 gene encodes a protein containing a Josephin domain. Josephin domain-containing proteins are deubiquitinating enzymes which catalyze the hydrolysis of the bond between the C-terminal glycine of the ubiquitin peptide and protein substrates. The expression of JOSD2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.