Companies / Creative Biolabs / Anti-CD19 scFv h(41BB-CD3ζ) CARNK, pCDCAR1
Creative Biolabs

Anti-CD19 scFv h(41BB-CD3ζ) CARNK, pCDCAR1 | Creative Biolabs

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The vector of anti-CD19 chimeric antigen receptor(CAR) is constructed for the engineering of NK cells to target Human CD19. The NK cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD19 antibody linked to CD137 (4-1BB) and CD3-zeta signaling domains. And the vector product was designed for the treatment of chronic lymphocytic leukemia (CLL).

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