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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Anti-MAGE3 (21B4) ICD(CD147) CAR THP1 Cell Line | Creative Biolabs
The anti-MAGE3 chimeric antigen receptor (CAR) THP1 cell line is a stable cell line developed using anti-MAGE3 CAR lentivirus transfection. This transfected CAR lentiviral vector is constructed to express a scfv of anti-MAGE3 antibody (21B4) linked to CD147 signaling domains.The anti-MAGE3 CAR engineered THP1 cells can be used to be differentiated into macrophage cells for in vitro or in vivo phagocytosis studies. This CAR-THP1 cell line product can be used for the researches of NSCLC (MAGE-A3/6), metastatic melanoma (70% MAGE-A1-5).
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