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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Anti-Mesothelin (SS1) ICD(CD147) CAR THP1 Cell Line | Creative Biolabs
The anti-Mesothelin chimeric antigen receptor (CAR) THP1 cell line is a stable cell line developed using anti-Mesothelin CAR lentivirus transfection. This transfected CAR lentiviral vector is constructed to express a scfv of anti-Mesothelin antibody (SS1) linked to CD147 signaling domains.The anti-Mesothelin CAR engineered THP1 cells can be used to be differentiated into macrophage cells for in vitro or in vivo phagocytosis studies. This CAR-THP1 cell line product can be used for the researches of PDA (up to 100%), MPM (85%), Ovarian (70%), lung adenocarcinoma (53%, advanced; 69%, early stage), GBM.
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