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Creative Biolabs

Human Tna?ve cells | Creative Biolabs

T-cells are functionally divided into helper T-cells, which are CD4+ CD8- (""T4""), and cytotoxic T-cells, which are CD8+ CD4- (""T8"").
T cells can also be divided based on differentiation status into 4 subsets:
1. Na?ve (""Tn "", containing Tscm), which are CD27+ CCR7+ CD45RO
2. Central-memory (""Tcm""), which are CD27+ CCR7+ CD45RO+
3. Effector-memory (""Tem""), which are CD27- CCR7- CD45RO+
4. Effector (""Teff""), which are CD27- CCR7- CD45RO-
Human PBMC are separated into 4 subsets using antibodies and magnetic beads. The subsets were: CD4+CD8- T cells (T4), CD8+CD4- T cells (T8), CD4+ central memory T cells (Tcm) and CD4+ effector-memory T cells (Tem). Immediately after isolation, the subsets and the PBMC were analyzed by flow
cytometry for the composition of the subsets.

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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.