Name: "Anti-CD45 (4122) h(ICOS-4-1BB-CD3_) CAR, pCDCAR1"
Availability: InStock

"Anti-CD45 (4122) h(ICOS-4-1BB-CD3_) CAR, pCDCAR1" | Creative Biolabs

Creative biolabs has developed Lentiviral CAR vector pCDCAR1 CD45 (4122) h(ICOSBB_), which is constructed for the engineering of T cells to target human CD45. The T cells are genetically modified through transduction with a Lentiviral vector expressing scFv of anti-CD45 antibody linked to a CD28 transmembrane domain/ endodomain and OX40, CD3-zeta signaling domains. And the vector product was designed for the treatment of autoimmune disease.