Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
The vector of anti-GPC1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to simultaneously target two epitopes of human GPC1. The T cells are genetically modified through transduction with a lentiviral vector expressing anti-GPC1 VHH1 and VHH2 linked to CD28 and CD3_ signaling domains. And the biepitope CAR targeting T cells can be used for the treatment of Sarcoma.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.