Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
The Anti-L1CAM (X11X236) h(28OX_) CAR-Jurkat-NFAT-Luc cell line is a stable cell line derived from anti-L1CAM CAR lentivirus transduction using Jurkat-NFAT-luciferase cell as effector cell. This transduced CAR lentiviral vector was constructed to express scFv of an anti-L1CAM antibody linked to the CD28-OX40-CD3_ signaling domains. The CAR-Jurkat cell line constitutively expressing the firefly luciferase gene under the control of NFAT response elements to facilitate subsequent research. And the recombinant cell product targeted L1CAM for CAR-T studies in human various cancers and inflammatory diseases.
Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.