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Creative Biolabs is the leading custom service provider with extensive experience in various antibody production and engineering fields.
Creative Biolabs
Anti-PSA (X11X35) h(ICOS-4-1BB-CD3_) CAR-Jurkat-NFAT-Luc | Creative Biolabs
The Anti-PSA (X11X35) h(ICOSBB_) CAR-Jurkat-NFAT-Luc cell line is a stable cell line derived from anti-PSA CAR lentivirus transduction using Jurkat-NFAT-luciferase cell as effector cell. This transduced CAR lentiviral vector was constructed to express scFv of an anti-PSA antibody linked to the ICOS-41BB-CD3_ signaling domains. The CAR-Jurkat cell line constitutively expressing the firefly luciferase gene under the control of NFAT response elements to facilitate subsequent research. And the recombinant cell product targeted PSA for CAR-T studies in human Renal cell carcinoma.
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