Labroots is excited to present the 12th Annual Event in the Neuroscience Virtual Event Series , to be broadcasted live on March 6th, 2024. This distinguished, online-only, event is free to a...
Infant motor development is measured clinically using short, subjective, observational scales. While these scales are useful, they have limitations. They provide us with a “snapshot&rd...
This talk will present the methodology of using the guided ultrasonic waves generated by the rodent to track its physiology, behavior, and psychological state. When behaving in an environmen...
A core goal of neuroscience is to understand how the brain adaptively orchestrates movements to execute complex behaviors. Quantifying behavioral dynamics, however, has historically been pro...
Many nonhuman primate species show sex differences in behavior, which suggests that there may also be sex differences in brain organization. In order to better understand the evolution of se...
How do the cognitive and physiological traits of individuals translate into real-world group dynamics? There is an empirical and theoretical gap between understanding individual-level proces...
Our ability to record large-scale neural and behavioral data has substantially improved in the last decade. However, the inference of quantitative dynamical models for cognition and motor co...
Transdisciplinary knowledge producing teams (TDKPTs) dedicate their efforts to solving wicked problems. Successful TDKPTs embody characteristics of complex adaptive systems (CAS) and exempli...
Many behaviors are learned through trial and error by matching performance to internal goals, yet neural mechanisms of performance evaluation remain poorly understood. We recorded basal gang...
Speech neuroprostheses have the potential to restore communication to people living with paralysis, but naturalistic speed and expressivity are elusive. Here we use high-density surface reco...
Mental health is a multidimensional challenge, marked by rapid brain changes and essential interpersonal relationships. This complicates the application of traditional statistical methods an...
The ultimate goal of neuroscience is to understand and explain real-world behavior in terms of brain activity, and to use these insights to develop therapeutic approaches for neural disorder...
Vestibular sensation anchors our perception of the environment and is crucial for maintaining balance during locomotion. Vertebrate animals use the evolutionarily conserved vestibular system...
Robots are useful tools for studying the nervous system and its control of body mechanics because they can be used to perform experiments that would be difficult to perform with an animal. F...
Social interactions are essential for the survival of social animals. Across species the medial prefrontal cortex (mPFC) has been identified as a hub of social cognition. In mouse models we...
Drug discovery programs require a robust panel of models and assays to identify and validate drug targets, support compound optimisation, and run mechanistic studies. Fully human in vitro mo...
DBS for obsessive-compulsive disorder (OCD) achieves clinical benefit in 66% of treatment-resistant patients. However, there is still a lack of a fundamental understanding of the neurophysio...
Precision medicine in solid tumors is transforming the testing and treatment of cancer. You can be part of this exciting field by joining our one-day virtual event. Some of the highlights of...
In recent years, small volume biopsies have been increasingly utilized for diagnosis of tumors in both primary and recurrent settings. Concomitantly, the numbers of ancillary studies for cha...
Labroots and the Drug Discovery planning committee are pleased to announce its 7th Annual Event in the Drug Discovery & Development Virtual Event Series . Labroots will host this online-...
mRNA‑based products are rapidly growing in the biotherapeutics space. Important considerations need to be made to develop a process for mRNA synthesis that consistently generates high‑yield...
Interoceptive signals dynamically interact with the environment to shape appropriate defensive behaviors. Neurons in the hypothalamus regulate internal states, such as thirst and circadian r...
This presentation explores the pharmacokinetics (PK) and pharmacodynamics (PD) of β-lactam antibiotic dosing, particularly in ICU patients. To optimize PK/PD targets, two strategies are...
Multiplex immunofluorescence is a powerful tool for phenotyping cells from a single tissue slide, while preserving spatial context. The MultiOmyxTM platform, offered as an end to end service...
Across many cancers, mortality is associated with metastasis and acquired drug resistance, both of which often manifest in recurrent disease. Central to these phenomena is epithelial to mese...
Current cancer research is hindered by the limitations of existing experimental systems, which fall short in demonstrating concordance with human studies. In this way, we aim to develop mode...
Spatial analysis of protein or gene expression is vital to understanding the distribution, phenotypes, and interactions between cells within tumor microenvironment (TME). Traditionally, mult...
Central Nervous System (CNS) therapies have significantly progressed in the last decade, propelled by emerging treatment modalities including gene therapies. Neurological indications remain...
NAFLD (non-alcoholic fatty liver disease) is a global epidemic that affects 25% of the world’s population, with its epicentre in the West. Twenty percent of NAFLD patients go on to dev...
Learning Objectives: 1. Summarize the benefits and challenges of current preclinical methods in drug discovery and development. 2. Review new alternative methodologies (NAMs) and microphysio...
Proliferation biomarkers are proteins that are up-regulated in growing cells. Immunological staining of tumor tissue can provide an indication of the aggressivity of the tumor and provide in...
Labroots is excited to present the 12th Annual Event in the Neuroscience Virtual Event Series , to be broadcasted live on March 6th, 2024. This distinguished, online-only, event is free to a...
